BACKGROUND: Flavobacterium meningosepticum is an uncommon pathogen causing nosocomial pneumonia and meningitis in newborns. It is usually. Elizabethkingia meningoseptica is a gram-negative rod-shaped bacterium widely distributed in . Flavobacterium meningosepticum King, (Approved Lists, ); Chryseobacterium meningosepticum (King, ) Vandamme et al., . Flavobacterium meningosepticum is a gram negative, opportunistic organism which has been implicated in a number of outbreaks of sepsis and meningitis in.
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Subsequent development of resistance to erythromycin prompted the use of intravenous and intraventricular rifamycin, which eventually resulted in cure. Subacute bacterial endocarditis due to Flavobacterium meningosepticum. Both the cases were referred from outside facilities and were not associated with outbreaks in the referring hospitals.
Exchange transfusion was performed and the baby was mechanically ventilated. Associated Data Supplementary Materials.
Flavobacterium meningosepticum bacteremia: an analysis of 16 cases.
Glucose and calcium gluconate were given intravenously. Flavobacterium meningosepticum meningitia ins newborn infant. In this study, we report the crystal structure meningospticum recombinant GA from Flavobacterium meningosepticum.
Automated bacterial identification system results should be observed with caution, especially when a patient with gram-negative bacteremia does not improve with broad-spectrum antibiotic therapy, because several bacteria, including Aeromonas salmonicida mistaken by ID32 GN  and Sphingobacterium spp. Bruun as two key authorities on this bacterium.
Neonatal meningitis caused by flavobacterium meningosepticum. Meningitis in a new born due to Flavobacterium meningosepticum.
In other projects Wikispecies. Flavobacterium meningosepticum from neonatal flavobcterium. Support Center Support Center. Some of the outbreaks have been linked to sources like contaminated lipid stock bottles, contaminated venous catheter lines and nutritional solution, and tap water. Glycosylasparaginase GA is a member of a novel family of N-terminal nucleophile hydrolases that catalytically use an N-terminal residue as both a polarizing base and a nucleophile.
Hypoalbuminemia, increased pulse rate at the onset of infection, and central venous line infection were associated with a poor outcome.
The other eight patients suffered nosocomial bacteremia within a mean period of Neonatal meningitis caused by new serotype of Flavobacterium meningo-septicum. Vancomycin sensitivity clearing around disk and colistin resistance may lead to mistaking this organism as gram positive. Indian J Med Res.
National Center for Biotechnology InformationU. Treatment with intraventricular erythromycin. The patient had an apneic episode following which he was transferred to AKUH. There have been very few cases reported from the South Asian subcontinene 7. In the bacterial GA crystals, we observe a heterotetrameric structure flavobacherium to that found in the human structure, as well as that observed in solution for eukaryotic glycosylasparaginases.
There were 10 men and six women, with a mean age of The organism was resistant to penicillins, cephalosporins, aztreonam, imipenem, aminoglycosides and macrolides. If you would like to receive our newsletter and become a supporter of this well deserving charity please click on the subscription link at the bottom of our website.
A deficiency of GA results in the human genetic disorder known as aspartylglycosaminuria. Therefore, it is necessary to know the full spectrum of the infection in adults and to identify effective antimicrobial agents. Subcommittee on the taxonomy of Flavobacterium and Cytophaga -like bacteria. Research articles conducted on animals, will not be considered for processing or publication in the JPMA. View more in-depth experimental data.
International Journal of Systematic and Evolutionary Microbiology. The Aga Khan University Hospital in Karachi has neonatal tertiary care facilities and consequently receives patients from a large referral population. All except one patient survived without sequelae.
Eighteen isolates of F meningosepticum were identified from 16 patients. Wet raised colonies with clear margin and characteristic smell after culturing on blood agar. You can also find us on social media:.
Antimicrobial treatment of Flavobacterium meningosepticum infection.
The charity was founded over 30 years ago after our founder Trustee, Val Jourdan visited the region as a physiotherapist. Experimental Data Snapshot Method: You can also find us on social media: Cefotaxime and Amikacin were continued after blood and CSF cultures. Flavobacterium meningosepticum King Chryseobacterium meningosepticum King Vandamme et al.
Although the organism was resistant to rifampicin and ceftazidime on disc diffusion testing, ceftizoxime was not readily available and an interim therapy was initiated with these drugs. Meningitis caused by an unclassified gram-negative bacterium in newborn infants.