Visualizing the next generation of sequencing data with GenomeView .. .. A .. Why inverse proteins are relatively abundant, J.-C. Nebel and C. Walawage, Protein & Peptide Letters, 17(7), Michal Nánási ([email protected] ) Website: (free download, tutorials, manual, . Next generation sequencing presents new challenges in large scale data at the European Conference of Computational Biology (ECCB) , Ghent. Tutorials, workshops and seminars To do bioinformatics well, you need to learn 3 things. ECCB Next-gen sequencing Tutorial (Thomas [email protected]).

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Next generation sequencing | Taverna

The type and volume of the data produced by next-generation sequencing machines presents many previously unseen informatics challenges. The 48 accepted papers are included in this special issue.

The annotation of the non-coding genome with gene regulatory function is lagging far behind the annotation of protein-coding genes and improved annotation will depend both on deeper biological insight into cis-regulatory logic and on more efficient computational prediction algorithms. Ruben Kok Dutch Techcentre for Life Sciences had a decisive role in the Local Steering Committee, while Celia van Gelder is thanked once more for her support also in organisational matters.

The review form explicitly differentiated between impact and suitability for ECCB on the one hand, and scientific quality and reproducibility on the other. This tutorial will help people who are getting started on next-gen sequencing get an net-gen of the tools, flows, and procedures that they may need to set up to handle this data.

Thanks to our academic and commercial sponsors and to the careful control of conference costs, we could satisfy about two-thirds of the requests. He will start an assistant-professorship at the University of Leuven in October. We thank all those who provided financial support to the conference. Sponsored Talks enable sponsors to showcase their innovations in computational biology and to highlight their scientific value.

The ECCB edition features keynote lectures by distinguished speakers. Current methods and applications for regulatory sequence analysis Tutorial 4: Email alerts New issue alert.

The ECCB science has been in the able hands of the following individuals, whose painstaking efforts have been vital: It is therefore important for all protein structure bioinformaticians to be able to evaluate the quality of the structures used in their studies and to know when it might be beneficial to ask an NMR spectroscopist or X-ray crystallographer to help bring an old file up to today’s standards.


Each of you will bring something to the conference in terms of scientific contributions, applications, oral or poster presentations and discussions. Recent data obtained by high-throughput experiments accelerate the genome-wide identification of regulatory elements but also provide additional bioinformatics challenges. Following the call for Proceedings papers, we received submissions.

BioinformaticsVolume 32, Issue 17, 1 SeptemberPages i—i, https: All original research papers that had been published in peer-review journals between 1 March,and the submission deadline of 29 Marchwere eligible to be presented as a Highlight talk.

Next generation sequencing

To present a more unified view of where the science has gone over recent years, new to ECCB this year is that the conference presentations are divided over five broad themes: We are grateful to the ECCB steering committee for their support and contribution to the organization of the conference. After thorough consideration and discussion, the ECCB theme co- chairs selected 24 proposals out of 71 submissions, mainly on the criteria of compatibility with the ECCB objectives, wide impact in the life sciences and the tutlrial for attracting a large audience to the conference.

In the light of these developments, this tutorial will focus on bioinformatics methods to predict cis-regulatory elements and to aid the process of regulatory annotation. Today’s software and CPU time availability on clusters, super computers, and the grid allow for easy improvement of old files. Finally, all these efforts would be meaningless without the many participants from all over the world. It coordinates, integrates and sustains bioinformatics resources across its member states, enabling users in academia and industry to access vital data, tools, standards, compute and training services for research.

The Semantic Web is a set of technologies, or a framework, which rccb designed to make data integration possible via the web, with the addition of a precise semantic characterization of entities and relations ontologies. We believe that for all of the rejected submissions, the reviewers provided high-quality reports. Working with next-generation sequencing data Tutorial 2: Each tutorial sequenccing offer participants an opportunity to learn about new areas of bioinformatics research, to get an introduction to important established topics, or to develop advanced skills in areas they are already familiar with.

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The ECCB organizing committee congratulates all these dynamic young scientists for their enthusiasm, which is essential to the future of research in computational biology. This workshop will teach the participants how to use a series of protein structure validation tools and how to interpret the results.

The workshops, running all but one for a single day, provide participants with an informal setting to discuss technical issues, exchange research ideas, and to share practical experiences on a range of focused or emerging topics in computational biology.

Participants will be provided with an overview of existing resources databases, tools and methods for detecting cis-regulatory elements in genome sequences, and generate testable hypotheses about the binding specificity of transcription factors motifs discoverytheir precise binding locations binding site predictionand their target genes target identificationand go towards regulatory networks.

He subsequently tutoriaal to the Pathogen Genomics group at the Wellcome Trust Sanger Institute to work on sequence assembly of several pathogens such as Plasmodium falciparum strains, Trypanosoma brucei, and several other pathogen genomes.

The Applications Track features 11 presentations, which were selected out of 31 submissions. We received more than eighty applications for travel fellowships from young scientists with tutoeial oral or poster presentation.

These rankings were subsequently used to assign papers to themes and to arrive at an optimally balanced distribution of submissions over the themes. Submissions to this track should cross the boundaries of traditional academic science, or show developments that are directly relevant beyond academia or have potential for it. The origins of problems are discussed as well nfxt-gen their importance for follow up studies.