5 jul. 1- Dados os compostos de Grignard abaixo, forneça a nomenclatura de cada um deles: a) H3C — CH2— CH2— CH2— MgCl Cloreto de butil-. Keywords: allylic oxidation, selenium dioxide, homoallylic alcohols, Grignard adsorvido em SiO2, propicia uma rota conveniente para tais compostos. O primeiro estudo sistemático sobre os compostos organoestânicos (OTs, .. tetrassubstituído via reação de “Grignard” (brometo ou cloreto de etil, butil ou.
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The extracts were dried over MgSO 4filtered and the solvent was removed under reduced pressure by rotatory evaporation. The solvent was removed under reduced pressure and the residue was diluted with ether 50 mL and water 30 mL and extracted with ether 2×50 mL.
To a stirred solution of 14 3.
After 30 min, geranyl bromide 2. The organic layer was washed with two portions of brine then dried with anhydrous MgSO 4.
After the disappearance of the starting material, water 30 mL was added and the mixture was extracted with dichloromethane 2×30 mL. Rgignard on occasion of his 60 th birthday. The occurrence and the effects of organotin compounds OTs have been studied since a grignrad time, due to their widespread use and deleterious effects. New York,p. In a three necked round bottom flask, tert -butyldimethylsilyl 2-iodophenol ether 11 3. The solvent was removed under vacuum and the residue was diluted in ether 50 mL and water 30 mLthen extracted with ether 2×30 mLdried over MgSO 4 and filtered, and then the solvent was removed under reduced pressure.
A suspension of selenium oxide 0. February 4, Published on the web: The reaction was cooled, a saturated solution of NH 4 Cl was added, the solutions was extracted with ether 3×50 mLdried over MgSO 4filtered and the solvent was removed under reduced pressure by rotatory evaporation. To stirred solution of 1. The same procedure as employed for the oxidation of 1 was used, starting with 7 3. The chosen protecting groups clearly influence the oxidation process.
A solution of 2. After allowing the reaction mixture to reach ambient temperature, CuI was added followed by the addition of allylic alcohol 2. This result was still not satisfactory so we tried a different approach. The Sharpless conditions for oxidation of geranyl acetate employs 0.
Organoclorado – Wikipedia, a enciclopedia libre
How to cite this article. The same procedure as employed for the coupling of 11 and compostl was usedstarting with tert -butyldimethylsilyl 2-iodophenol ether 11 3. Tetrahydro-2 H pyranyl ether 7 3. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.
Then BuLi in hexane 2.
Scheme 2 shows the first attempt. New York,vol. Economic Entomology81 Geranyl bromide 4 was necessary in the next steps and its preparation although it is commercially available was achieved after some attempts in order to optimize the conditions for getting high yield.
Naturstoffe22 Some OTs are used as pesticides in crops, or as biocides in antifouling paints, applied in the ship hulls to avoid attachment and growth of tube worms, mussels and barnacles.
Economic Entomology79 Services on Demand Journal. In this work we reported a revision study on the history of OTs and the techniques developed for its assessment and control.
How to cite this article. Preparation of aromatic geraniol analogues via a Cu I -mediated Grignard coupling. Completion of the reactions was established by TLC analysis. The ether phase was washed with water 30 mLgrivnard with brine 2×30 mLdried over MgSO 4filtered and the solvent was removed under reduced pressure by rotatory evaporation.
To a solution of 2-iodophenol 2. Our target was to obtain 2-[ 2 E ,6 E -3,7-dimethylhydroxy-2,6-octadienyl]phenol 9 by optimizing the coupling of geranyl acetate derivatives with more appropriate reagent O -protected 2-iodophenol. To a solution of 10 3. The mixture was stirred for 48 h.
After stirring for 15 min at room temperature, cold pentane 25 mL was added, and the organic layer was washed with cold water, extracted with pentane 2×25 mL and then washed with brine.