Explanation for the ‘células intersticiales de Cajal’ phrase in the dictionary. What does the ‘células intersticiales de Cajal’ phrase mean? Definitions. The interstitial cell of Cajal (ICC) is a type of interstitial cell found in the gastrointestinal tract. There are different types with different functions. Myenteric Interstitial. ORIGINAL ARTICLES. Interstitial cells of Cajal and intestinal function in Trinidadian children. Células intersticiales de Cajal y función intestinal en niños.

Author: Murisar Mezisar
Country: Republic of Macedonia
Language: English (Spanish)
Genre: Technology
Published (Last): 12 July 2014
Pages: 204
PDF File Size: 2.99 Mb
ePub File Size: 4.26 Mb
ISBN: 923-8-65563-210-5
Downloads: 49298
Price: Free* [*Free Regsitration Required]
Uploader: Moogusar

Cientificos (Spanish)

Magnification of 40x was used over an area of 1mm2 per compartment. Are you a health professional able to prescribe or dispense drugs? The distribution of these cells is difficult to study with light caal and a strong case was originally made for the use of transmission electron microscopy for their definitive identification 4.

The ICCs, thus stained, appeared as thin elongated cells with short processes. RESULTS The correlation of ICC counts for the individual layers of the bowel wall showed some divergence between the two observers, and clulas, comparison of cell counts for each bowel layer was not pursued.

These details are summarized in Table 2. Full thickness biopsies taken from the sigmoid colon stoma were available from two children, aged 11 and 20 months, with ARM at the time of restoration of bowel continuity.


This may be feasible even in developing countries where chronic disorders of bowel motility, resistant to conventional management, are a frequent basis for referral to specialist clinics.


Variations in the density and distribution of ICCs have been demonstrated in several clinical conditions and this investigation has cxjal a reduced density of these cells in the aganglionic bowel of the majority of patients affected by Hirschsprung’s disease HD. Interzticiales Smooth Muscle Res. Girls appeared to be more consistently affected by reduced ICC counts in aganglionic bowel but this observation is compromised by the fact that all of the rectal specimens were derived from female patients.

Interstitial cell of Cajal – Wikidata

Paseo de la Castellana Distribution of c-Kit immunopositive cells in normal human colon and in Hirschsprung’s disease. The tissue blocks of three of the aganglionic biopsies either could not be located or had interstiviales tissue available for further processing. The Impact Factor intersitciales the average number of citations received in a particular year by papers published in the journal during the two receding years. ICC are also critical in the propagation of electrical slow waves.

Print Send to a friend Export reference Mendeley Statistics. Subscribe to our Newsletter. J Pediatr Surg ; Cell counts were carried out in the submucosa, myenteric plexus and muscular layers of bowel wall by two independent observers both experienced histopathologists.

In the present work one sets out to study the cellularity and its modifications, and the presence of the interstitial cells Cajal in the human pineal gland, in different stages from the life. Nine issues are crlulas each year, including mostly originals, reviews and consensus documents.

Retrieved from ” https: Altered distribution of interstitial cells of Cajal in Hirschsprung disease. Segments of bowel wall excised from eight children with HD, three controls and two children with ARM were immunostained with c-Kit primary antibody.


Interstitial cell of Cajal – Wikipedia

In conclusion the results changes of the cellularity of the human pineal gland are demonstrated, that they increase of size conforms increases the age until the young adult. These discoveries have been the subject of interstickales alternative interpretations: Interstitial cells of Cajal and intestinal function in Trinidadian children.

Celulsa Pathol Lab Med ; ICC form a network through which slow wave activity can intersticixles. Our two patients with ARM had normal density of these cells as has been more commonly reported 7, J Pediatr Surg Intramuscular Interstitial cells of Cajal ICC-IM are involved in the stimulation of smooth muscle cells, neurotransmitters act through them.

One of the latter continued to have a daily average of two normal bowel motions during a follow-up period of more than two years following completion of surgery.

Motor neurotransmission in the gut has been shown to occur via synaptic-like contacts between varicose nerve terminals and intramuscular ICCs ICC-M’s. Update on pulmonary arterial Users should refer to the original published version of the material for the full abstract. To counteract the difficulties associated with studying their distribution by light microscopy, c-Kit cells and synapses can now cleulas visualized by immunohistochemical methods involving the use of commercially available monoclonal antibodies 4.