Baccharis dracunculifolia, the main source of green propolis, exhibits potent antioxidant activity and prevents oxidative mitochondrial damage. PDF | The present study had as its objective to evaluate the antibacterial and antibiotic modulatory activity of the Baccharis dracunculifolia (DC). This study aimed to analyze the insecticidal potential of ethanol extract of Baccharis dracunculifolia DC, on Spodoptera frugiperda Smith, (Noctuidae) and.

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Leishmaniasis has a broad spectrum of clinical manifestations based on the causative species and the immunological status of the host.

This experiment was run at least three times, cracunculifolia the MICs in the presence and the absence of ergosterol were determined simultaneously. The substances were dissolved in perdeuterated solvents containing 0. Several Baccharis species have been extensively used in folk medicine for the treatment and prevention of baccharsi, inflammation, diabetes, and stomach, liver and prostate diseases [ 6 ].

Trypanocidal and antileukaemic effects of the essential oils of Hagenia abyssinica, Leonotis ocymifolia, Moringa stenopetalaand their main individual constituents. Only caryophyllene oxide showed differences in the MIC values against Pb18 when the medium was supplemented with ergosterol, which suggested that the compound interacts with ergosterol.

After the unbound dye was washed out, the stained protein was dissolved with drafunculifolia mM Tris, and the absorbance was measured at a wavelength of nm.


Essencial oils of Baccharis salicifolia, B. The arrow in 9 shows the depression that occurred in the P. Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Dracunclifolia tetramera Hauman. It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. The authors alone are responsible for the content and the writing of the paper. In addition, a study by Johann et al.

Trichloroacetic acid was added to each well to precipitate the proteins, which were stained with sulphorhodamine B. We isolated the following four compounds Fig.

Interestingly, the hexane fraction displayed minimum inhibitory concentration MIC values ranging from 7. The present study is the first report the antifungal activities, the biological activities against tumor cells and the leishmanicidal effects of four compounds isolated from the aerial parts of Baccharis dracunculifolia.

The highest MIC values for trans-nerolidol, methyl linolenate, the hexanic fraction and amphotericin B were different. Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer Dracuncupifolia cells.

The authors report no conflicts of interest. Paracoccidioides brasiliensis dracuncuifolia paracoccidioidomycosis: All of the samples were tested in duplicate, and the experiments were repeated at least once.

The treatment of choice is a pentavalent antimony sodium stibogluconate [Pentostam] or meglumine antimoniate [Glucantime]both of which are parenteral drugs that are moderately toxic [ 8 ].


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Ursolic acid was active in the cytotoxic assays and showed leishmanicidal activity. The tests were performed in triplicate in at least two independent experiments. We also added 10 ml of the solution containing the samples and the control drug 0. Inhibitory effect of terpene bacchzris on the growth of Babesia parasites.

Amphotericin B was used as the control drug.

Cell wall analysis of an adenine-requiring mutant of the yeast-like form of Paracoccidioides brasiliensis strain IVIC Pb9. Asteraceae against Paracoccidioides brasiliensis Susana Johann. G nero Baccharis Asteraceae: Three of the isolated compounds i.

Baccharis dracunculifolia DC. — The Plant List

Fractions of the hexanic extracts were obtained using chromatographic procedures and assessed using an antifungal assay with Paracoccidioides brasiliensis Pb18tumor cell lines and amastigote forms of Leishmania, L. Analgesic and anti-inflammatory activity of caryophyllene oxide from Annona squamosa L. Interestingly, caryophyllene oxide was the only isolated substance that had its MIC value increased in the presence of exogenous ergosterol.