Resumen. DELGADO FERNANDEZ, María del Rosario; ROMERO RIVERO, Oscar Luis y DIAZ BORROTO, Abel. Central insipid diabetes: presentation of a case. Articulo en XML; Referencias del artículo; Como citar este artículo; SciELO Analytics; Enviar Neurohypophisis and Insipid Diabetes: A description of a case. Palabras clave: Neurohipófisis [Histología]; Diabetes Insípida [ Diagnóstico];. Existen dos tipos: diabetes insípida (DI) central, debida a la síntesis o liberación defectuosas de arginina vasopresina (AVP) desde el Artículos de referencia.

Author: Nak Dabei
Country: Poland
Language: English (Spanish)
Genre: Education
Published (Last): 24 July 2009
Pages: 190
PDF File Size: 4.61 Mb
ePub File Size: 2.53 Mb
ISBN: 995-5-15571-341-2
Downloads: 5624
Price: Free* [*Free Regsitration Required]
Uploader: Bralmaran

Am J Physiol Renal Physiol. Hospital Universitario Vall d’Hebron.

Among the different groups of patients with nephrogenic diabetes insipidus due to a secondary interstitial tubular disease, one of the most important is that caused by insipjda nephropathy which presents in children with severe malnutrition.

Therefore, fluid intake is fundamental to prevent the deleterious effects of repeated episodes of dehydration. With these urine samples the osmolality and density and the amount of urine will be determined. Surg Neurol ; Proliferation in pituitary adenomas: Ijsipida journal’s production is being transferred to another publisher. Sign up for a FREE trial.

The current state of affairs. The shortage or deficit of antidiuretic hormones provokes the elimination of a great volumen of hypotonic diluted and tasteless urine; this disorder is known as insipid diabetes. Estudio prospectivo de una serie de 23 casos.

When adequate stimuli are received, the hormone is artuculos together with neurophysin by means of exocytosis. Adv Neurol ; Persistent polyuria can cause the development of mega bladder, hydroureter and hydronephrosis. J Clin Endocrinol Metab ; Clin Neurosurg ; In the former, the patient generally, because of psychological disorders, ingests large quantities of water and other fluids, which causes a compensatory polyuria and a clinical picture insi;ida to diabetes insipidus is seen, but inwipida completely affecting the power of renal concentration.

Diabetes insípida central: presentación de un caso

Diabetes insipidus is a disease characterized by the elimination of high volumes of very dilute urine. Also observed are vomiting, constipation and lack of weight or height gain due to decreased ingestion of nutrients as a result of the polydipsia.


Take a look at our subscription options. In contrast, insipid persistence of a lack of response corresponds to cases of nephrogenic diabetes insipidus Fig.

BMJ Best Practice

Different ways to open and close the tap. J Am Soc Nephrol. Finally, members of some families with the dominant autosomal variant of diabetes insipidus have been studied, in whom mutations of the gene of the aquaporin-2 has also been identified. With this test, neurogenic diabetes insipidus will be differentiated from nephrogenic.

Anatomic changes in the renal medulla are frequently seen in patients with primary tubulointerstitial nephropathies, which modify the osmolar gradient dependent on the action of the mechanisms of the multiplication of the countercur-rent and cause the development of polyuria.

If your hospital, university, trust or other institution provides access to Best Practice, log in via the appropriate link below: Materials, methods and results. From functional rescue to promising therapeutic strategies. In these cases, mutations of the gene that codify the action of aquaporin-2 AQP2 have been observed, which conditions the lack of response of the principal cells of the collecting tubules of the nephron to the action of the AVP.

Increase of serum concentrations of sodium, chloride and urea can be seen in the blood due to the negative balance of water and a tendency to serum hyperosmolality. It is described the case of an Insipid 30 year old female patient with a past history of a cronic mielocitic leukemia in her final stage who was also presenting at the moment polyuria 3to 7 lts in 24 hours.

Previous article Next article.

Subscription required

You can change the settings or obtain more information by clicking here. In older children, intense thirst is associated with polyuria with volumes of various liters, and that on occasion is manifested by enuresis, growth delays and anorexia occurs, with preference for intake of cold water.


The test is begun after 8 a.

When prostaglandins are administered, the effect of the thiazides decreases. Magnetic resonance imaging of the sella turcica and parasellar region. Urodynamic studies diabees a complacent bladder with slow and incomplete emptying, which exacerbates deterioration of renal function for which procedures such as cystostomy have been required to viabetes bladder emptying.

These cases allow to emphasize that studies of patients with nephrogenic diabetes insipidus and hydronephrosis should also rule out aggregated urinary obstructive causes.

Subscribe to our Newsletter.

There was a problem providing the content you requested

A clinical-radiographic evaluation with computed tomography. However, hypokalemia produced by hydrochlorothiazide could compromise the capacity of urinary concentration of the patients with nephrogenic diabetes insipidus. N Engl J Med. Transsphenoidal surgery of parasellar pituitary artichlos. En este estudio se incluyeron de forma prospectiva 23 pacientes en el periodo comprendido entre Mayo y Diciembre del Mean follow up was 15 months. Its synthesis is accompanied by the generation of a specific carrier protein called neurophysin II.

Figure 1 Action pathways of arginine vasopressin AVP in the collector tubule of the nephron cells. The first aquaporin was identified in the erythrocytes in and was called aquaporin It is a nine amino acid peptide with an annular structure and a disulfuric connection.

Purine-binding factor nm23 gene expression in pituitary tumors: Las variables cualitativas se resumieron mediante tablas de frecuencias con las frecuencias insiipda y absolutas. Se obtuvieron tablas resumen para todas las variables recogidas en el estudio.